Institute of Physiology

http://physiology.by/  
220072 Minsk, Academic St., 28

Methodology for conducting transcranial magnetic stimulation

COUNTRY OF ORIGIN

Belarus

IDENTIFIER

BO13205

PUBLISHED

2025-03-21

LAST UPDATE

2025-03-22

DEADLINE

Linked profile in other language
Responsible
Tatiana Khrustaleva
+375 17 378 1630
biblio@fizio.bas-net.by
Summary
The Institute of Physiology offers consumers services for the use of transcranial magnetic stimulation techniques for the treatment of general developmental disorders and specific developmental and speech disorders, including autism in children aged 3–9 years, under an outsourcing agreement and is seeking partners interested in a distribution services agreement.
Description
Treatment of general developmental disorders and specific developmental and speech disorders, including autism in children aged 3–9 years using the transcranial magnetic stimulation (TMS) method, which is based on the hardware effect of an alternating magnetic field on the patient's brain in order to modulate the excitability of brain structures and achieve a therapeutic effect. The course of treatment includes 10–30 procedures.

The method is designed for psychiatrists-narcologists, physiotherapists-narcologists, physiotherapists, functional diagnostics doctors of healthcare organizations providing medical care in inpatient and/or outpatient settings and/or day care departments.

Information is posted in the "Album of Promising Developments of Organizations of the National Academy of Sciences of Belarus for the Real Sector of the Economy" (2023), pp. 373-374. (in Russian)
Advantages and Innovations
There are TMS methods for treating adult patients. This method was developed for treating children and has no analogues in the Republic of Belarus. It is effective in 80% of patients with disorders of psychomotor development of various genesis, including autism. If the instructions are followed, the method is safe. If necessary, the location of the inductor is adjusted and/or the intensity of the stimulus used is reduced in accordance with the instructions for use.
Stage of development
Already on the market
Comments regarding stage of development
The method has been introduced into practical healthcare of the Republic of Belarus (Vitebsk Regional Clinical Center for Psychiatry and Narcology (07.08.2019); consultative and outpatient department of the State Institution "Republican Scientific and Practical Center for Mental Health" of the Ministry of Health of the Republic of Belarus (23.01.2020).
Funding source
State budged
Internal
IPR status
Exclusive rights
Other
Secret know-how
Comments regarding IPS status
Instructions for use "Method of treatment of general developmental disorders, specific disorders of speech and language development by transcranial magnetic stimulation" T. V. Dokukina, M. I. Tukalo, I. I. Khvostova, T. A. Mityukova, O. E. Polulyakh, O. Yu. Zakharevich, A. I. Martynenko, reg. No. 047-0419 dated 04.25 2019 (in Russian)
Sector group
BioChemTech
Healthcare

Client information

Type
R&D institution
Year established
1953
NACE keywords
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
Q.86.90 - Other human health activities
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute is a leading scientific institution coordinating physiological research in the Republic of Belarus.

The institute successfully carries out fundamental and applied research aimed at developing methods for the prevention and correction of pathological conditions of hypoxic, ischemic and inflammatory genesis, and develops new devices and methods for their therapeutic and prophylactic use. The main scientific activity of the departments is currently focused on studying the mechanisms of the formation of pathological conditions of the body (primarily hypoxic and neurodestructive) and substantiating new technologies for prevention, treatment and rehabilitation. Particular attention is paid to the development of complex methods for the treatment of malignant tumors using metabolic blockade effectors and high-intensity pulsed magnetic fields and methods for controlling the proliferation of tumor cells based on changes in the functional state of neuroreceptors in vitro and in vivo, as well as the development of a method for immunotherapy of patients suffering from pancreatic cancer. , using autologous dendritic cells primed with tumor antigens and elucidating new mechanisms of tumor formation, substantiation of prevention methods. Studies of the molecular mechanisms of proliferation, differentiation and oncogenesis are being carried out; physiological and therapeutic effect of physical factors and the development of new technologies of physiotherapy and physiotherapy equipment and experimental analysis of positive and negative aspects of the use of nanoparticles and heterocyclic compounds in biomedical technologies. The neurophysiological bases of dysregulation of the functions of internal organs during ischemia of the nervous tissue of various origins are being studied. Works on the physiology of nutrition and sports are being carried out. Preclinical studies of drugs and nanomaterials are underway. Research is being carried out on the safety of biosubstances, biotherapeutic agents, pharmacological complexes and medical products on the basis of agreements with manufacturing enterprises and research institutions. The staff of the Institute conducts research on the mechanisms of interaction between neurons and glial cells in normal and pathological conditions. The functional role of biological preparations (platelet-rich plasma, suspension of mitochondria, mesenchymal stem cells, etc.) in the activation of reparative processes in strokes and brain injuries, ischemia of the lower extremities is being studied. Methods for stable remote monitoring of vital human functions (heart, blood vessels, respiration, temperature, motor activity, brain activity) are being developed. Particular attention is paid to the study of the functional role of the extracellular matrix and stem cells in the development of neoplasms. Cell technologies are being developed for the treatment of malignant diseases. The Institute also evaluates the therapeutic and therapeutic-prophylactic properties of natural mineral waters and the effectiveness of pre- and probiotics - food, food supplements.

Close scientific cooperation is carried out with scientists from Russia, China and Uzbekistan.
Languages spoken
English
Russian

Information about partnership

Type of partnership considered
Distribution services agreement
Outsourcing agreement
Type and role of partner sought
Consumers interested in purchasing services for the use of transcranial magnetic stimulation for the treatment of general developmental disorders and specific developmental and speech disorders, including autism in children aged 3-9 years, under an outsourcing agreement.

Partners interested in purchasing services for the use of transcranial magnetic stimulation for the treatment of general developmental disorders and specific developmental and speech disorders, including autism in children aged 3-9 years, under a distribution services agreement.
Type and size of partner sought
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Sole proprietor

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