Institute of Biochemistry of Biologically Active Compounds

https://ibiochemistry.by/  
230030 Grodno, A. Tyzengauz Square, 7

Biologically active supplement for the prevention of complications of coronary heart disease

COUNTRY OF ORIGIN

Belarus

IDENTIFIER

BO13089

PUBLISHED

2025-03-06

LAST UPDATE

2025-03-08

DEADLINE

Linked profile in other language
Responsible
Elena Raduta
+375 15 255 9073
office@bioch.bas-net.by
Summary
The Institute of Biochemistry of Biologically Active Compounds offers consumers a biologically active supplement for the prevention of complications of coronary heart disease under a manufacturing agreement and/or a composition and formulation under a licensing agreement and is looking for partners to conclude a joint venture agreement.
Description
The composition and recipe of the biologically active supplement for protecting the heart from stress-induced myocardial infarctions have been developed and experimental studies have been conducted. Experimental studies have shown the high effect of the drug as a medicine.

The drug has cytoprotective, antioxidant, and anti-stress properties. It is recommended as an anti-stress agent for preventing stress-induced myocardial damage. The use of the drug will improve the quality of life of elderly people with coronary heart disease and reduce the number of myocardial infarctions.

In connection with the important task of import substitution in the field of pharmaceuticals in the Republic of Belarus, an original agent for preventing myocardial infarctions has been developed, which can be successfully produced in our country, replacing imported agents. The drug can be an export item.

Advantages and Innovations
The developed complex preparation has cytoprotective, antioxidant, anti-stress properties. It is recommended as an anti-stress agent for the prevention of stress-related myocardial damage. Administration of the preparation to rats in the model of experimental myocardial infarction reduces its area by 30%.

A prototype and technical instructions "Cardioprotective agent - prevention of myocardial infarction in ischemic heart disease" have been developed.

The effectiveness of the developed preparation has been tested and confirmed in experimental models of myocardial infarction on laboratory animals. A good cardioprotective effect (reduction of the area of ​​myocardial infarction) has been shown.

The developed preparation consists of a complex of biologically active substances used in pharmacology. Their bioavailability has been well studied. The production is not associated with the use of toxic substances, it is environmentally safe.

The composition of the biological supplement is innovative, there are no analogues.

Since the drug is highly effective, after preclinical and clinical trials, it may be produced as a medicine.
Stage of development
Field tested/evaluated (TRL8)
Comments regarding stage of development
The following business model of cooperation is proposed - joint production, registration of a pharmaceutical composition, possibly a dosage form. Additional studies may be conducted to expand the indications for use.
Funding source
State budged
Internal
IPR status
Exclusive rights
Patents granted
Secret know-how
Comments regarding IPS status
A remedy for the prevention of stress-induced myocardial damage: patent 18662 Republic of Belarus / V. V. Vinogradov, A. V. Tumanov, T. A. Vinogradova, Ya. R. Matsiuk, V. P. Andreev, I. K. Dremza, T. Yu. Smykovskaya, Yu. V. Yarotsky; date published: 26.06.2014. (in Russian)
Sector group
BioChemTech
Healthcare

Client information

Type
R&D institution
Year established
1970
NACE keywords
C.21.20 - Manufacture of pharmaceutical preparations
M.72.11 - Research and experimental development on biotechnology
M.74.90 - Other professional, scientific and technical activities n.e.c.
Q.86.90 - Other human health activities
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute of Biochemistry of Biologically Active Compounds is a leading scientific institution in the field of vitaminology, the study of molecular mechanisms of metabolism regulation in health and disease, the biochemistry of alcohol and drug addiction, neurochemistry and pharmacology.

The main areas of activity of the Institute:
- conducting fundamental and applied research aimed at studying the mechanisms of pathogenesis of liver diseases, cardiovascular and endocrine systems, alcohol addiction, pathological conditions associated with a deficiency of essential micronutrients and stress, in order to develop methods for their prevention, diagnosis and therapy;
- developing new innovative drugs, vitamin preparations, dietary supplements, as well as developing methods for isolating and purifying biologically active compounds from herbal medicinal raw materials, mastering their laboratory production for the needs of the pharmaceutical industry.

The Institute has developed unique technologies for obtaining dry extracts from medicinal plant materials and aromatic plants for use as components:
- in the production of dietary supplements,
- in the food industry,
- in the production of perfumes.

Custom production of products of deep processing and purification of extracts from plant raw materials for use as analytical standards is possible.

The Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus specializes in the development and production of diagnostic reagent kits for biochemical, hematological studies, reagent kits for the diagnosis of malignant neoplasms, infectious diseases, and the study of thyroid and reproductive functions.

The developed and manufactured kits allow obtaining consistently reproducible and accurate results at an affordable price. The company's strategy is aimed at innovative development. Reagent kits are used on semi-automatic and automatic laboratory systems, as well as in manual research. Adaptations for automatic analyzers can be provided additionally.

The Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus represents the world's leading manufacturers of reagents and materials in the Republic of Belarus, as well as its own products under the trademark "Institute of Biochemistry of Biologically Active Compounds of the National Academy of Sciences of Belarus".

The Institute’s mission is to meet the needs of scientists for high-quality reagents for scientific research at optimal prices in order to save budget funds.
Languages spoken
English
Russian

Information about partnership

Type of partnership considered
Joint venture agreement
License agreement
Manufacturing agreement
Type and role of partner sought
Consumers interested in purchasing a dietary supplement for the prevention of complications of coronary heart disease based on a manufacturing agreement and/or composition and formulation based on a licensing agreement.

Partners interested in purchasing a dietary supplement for the prevention of complications of coronary heart disease based on a joint venture agreement.
Type and size of partner sought
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Sole proprietor

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