Institute of Biophysics and Cell Engineering offers consumers services for the treatment of scars and age-related skin atrophy using dermal fibroblasts, including services using this method for adult patients in accordance with the medical license under an outsourcing agreement, and is looking for partners interested in a distribution services agreement.

The use of a biomedical cell product (BMCP) of dermal fibroblasts allows for the effective correction of atrophic cicatricial and age-related skin changes. The treatment uses the registered BMCP "Human dermal fibroblast culture" (TU BY 100217351.008-2019).

Developers: State Scientific Institution "Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus", State Educational Institution "Belarusian Medical Academy of Postgraduate Education".

Improved results in the treatment of scars and age-related skin atrophy (L90.5 and L57.4 according to ICD-10).

Scope - Medicine, dermatology, cosmetic surgery.

Consumers of the products: healthcare organizations providing medical care to patients in outpatient, inpatient, and day hospital settings.

More information about paid services for the population can be found on the Institute's website here.

Information is posted in Album of promising developments of the NAS of Belarus organizations for the real sector of the economy (2023), , стр. 292-293. (in Russian)

Scar and age-related skin atrophy treatment using dermal fibroblasts is performed only at the State Scientific Institution "Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus".

Medical services associated with cell therapy are provided to patients of the Republic of Belarus and foreign citizens.

The method has shown high efficiency, examination using the ANTERA 3D system - a positive effect of dermal fibroblasts on changing such parameters as scar texture, volume of scar depressions, volume of scar convexities and skin parameters such as the wrinkle deepening coefficient, skin texture, volume of skin depressions, pore volume. Assessment using the POSAS scale and the facial wrinkle assessment scale demonstrated an improvement in all indicators by at least 2 points. Immunohistochemical study of the expression of collagen I, collagen type III, showed a significant effect of autotransplantation of dermal fibroblasts on scar remodeling, synthesis of mature collagen.

The developed treatment method has shown good tolerability and safety for the patient. Side effects are rare and do not pose a health hazard. The method is environmentally safe.

The Department of Cell Therapy of the State Scientific Institution “Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus” provides medical services to the population on a paid basis.

Instructions for use "Method for treating scars and age-related skin atrophy using a biomedical cell product of dermal fibroblast culture", reg. No. 017-0321 dated 03/31/2021. (in Russian)

State Scientific Institution "Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus" is a leading scientific center in the field of biophysics.

Directions of fundamental and applied scientific research of the Institute.

In the field of medical biotechnology:
- genetic engineering - development of innovative biomedical cell products based on genetically modified cells;
- immunology and allergology - development of new methods of treatment and diagnosis of allergic diseases and immune dysfunctions;
- innovative vaccines - development of prototypes of domestic DNA and RNA vaccines for the prevention of viral diseases;
- new approaches to diagnostics - development of new technologies for early diagnosis of diseases and methods of personalized medicine aimed at improving the quality of human life;
- genome editing - somatic, induced pluripotent stem cells, which will allow treating diseases, including orphan, genetic;
- synthetic morphogenesis - including tissue and organ engineering.

In the field of bioinformatics technologies:
- structure-based design of new-generation drugs, development of innovative targeted antitumor and antiviral drugs using structural bioinformatics methods;
- synthesis of targeted drugs and their testing in vitro.

In the field of nanotheranostics and personalized nanomedicine:
- development of means of targeted delivery of new-generation therapeutic drugs using nanomaterials;
- development of biological nanochips for disease diagnostics;
- study of broad-spectrum biocompatible nanomaterials for the creation of biomedical cellular products, artificial organs, fundamentally new materials with antimicrobial, antiviral and anti-inflammatory activity.

Activities of the Center for Experimental and Applied Virology:
- culturing viruses, developing new methods for culturing human viruses to create diagnostic tools, medical prevention and treatment of viral diseases;
- creation of vaccine prototypes - against influenza (inactivated and recombinant), against African swine fever (vector), against pulmonary tuberculosis (therapeutic based on donor dendritic cells), innovative drugs against influenza.

Over the past years, the Institute has implemented a number of international contracts and agreements within the Framework Programs of the European Union, as well as with leading scientific centers, foundations, and societies.

Consumers interested in purchasing services for the treatment of scars and age-related skin atrophy using dermal fibroblasts, including services using this method for adult patients in accordance with the medical license based on an outsourcing agreement.

Partners interested in purchasing services for the treatment of scars and age-related skin atrophy using dermal fibroblasts, including services using this method for adult patients in accordance with the medical license under a distribution services agreement.