The Institute of Biophysics and Cell Engineering offers consumers services for the treatment of patients with long-term non-healing wounds and trophic ulcers using mesemchial stem cells and skin fibroblasts, including services using these methods for adult patients in accordance with the medical license under an outsourcing agreement, and is looking for partners interested in a distribution services agreement.

The use of the method of cell therapy for long-term non-healing wounds and trophic ulcers using mesenchymal stem cells or skin fibroblasts leads to stimulation of the healing processes of chronic wounds and ulcers, which significantly improves the quality of life of patients. The treatment uses registered biomedical cell products (BMCP) "Mesenchymal stem cells" (TU BY 100217351.004-2014 amend. No. 1) and "Human dermal fibroblast culture" (TU BY 100217351.008-2019).

Developers: State Scientific Institution "Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus", Educational Institution "Belarusian State Medical University".

The results of treatment of long-term non-healing wounds and trophic ulcers (L89, L97 and L98.4 according to ICD-10) have been improved.

Application area - medicine, oncology.

Product consumers - healthcare organizations providing medical care to patients in outpatient, inpatient and day hospital settings.

More information about paid services for the population can be found on the Institute's website here.

Information is posted in Album of promising developments of the NAS of Belarus organizations for the real sector of the economy (2023), , стр. 300-301. (in Russian)

The treatment method has no competitors in the Republic of Belarus, has a significant socio-economic effect and allows to eliminate microbial colonization of a chronic wound and stimulate reparative processes for the purpose of stable healing of the wound defect and improvement of the patient's quality of life.

Medical services associated with cell therapy are provided to patients of the Republic of Belarus and foreign citizens.

The developed method has shown high clinical effectiveness of treatment, good tolerability and safety of use for the patient.

Side effects are rare and do not pose a health hazard. The method is environmentally safe.

The Department of Cell Therapy of the State Scientific Institution “Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus” provides medical services to the population on a paid basis.

1. Instructions for use "Method of complex treatment of patients with long-term non-healing wounds using local LED phototherapy and autologous cultured dermal fibroblasts", reg. No. 066-1016 dated 17.02.2017. (in Russian)
2. Instructions for use "Method of treatment using autologous mesenchymal stem cells from adipose tissue in patients with trophic ulcers", reg. No. 093-0911 dated 18.11.2011. (in Russian)

State Scientific Institution "Institute of Biophysics and Cell Engineering of the National Academy of Sciences of Belarus" is a leading scientific center in the field of biophysics.

Directions of fundamental and applied scientific research of the Institute.

In the field of medical biotechnology:
- genetic engineering - development of innovative biomedical cell products based on genetically modified cells;
- immunology and allergology - development of new methods of treatment and diagnosis of allergic diseases and immune dysfunctions;
- innovative vaccines - development of prototypes of domestic DNA and RNA vaccines for the prevention of viral diseases;
- new approaches to diagnostics - development of new technologies for early diagnosis of diseases and methods of personalized medicine aimed at improving the quality of human life;
- genome editing - somatic, induced pluripotent stem cells, which will allow treating diseases, including orphan, genetic;
- synthetic morphogenesis - including tissue and organ engineering.

In the field of bioinformatics technologies:
- structure-based design of new-generation drugs, development of innovative targeted antitumor and antiviral drugs using structural bioinformatics methods;
- synthesis of targeted drugs and their testing in vitro.

In the field of nanotheranostics and personalized nanomedicine:
- development of means of targeted delivery of new-generation therapeutic drugs using nanomaterials;
- development of biological nanochips for disease diagnostics;
- study of broad-spectrum biocompatible nanomaterials for the creation of biomedical cellular products, artificial organs, fundamentally new materials with antimicrobial, antiviral and anti-inflammatory activity.

Activities of the Center for Experimental and Applied Virology:
- culturing viruses, developing new methods for culturing human viruses to create diagnostic tools, medical prevention and treatment of viral diseases;
- creation of vaccine prototypes - against influenza (inactivated and recombinant), against African swine fever (vector), against pulmonary tuberculosis (therapeutic based on donor dendritic cells), innovative drugs against influenza.

Over the past years, the Institute has implemented a number of international contracts and agreements within the Framework Programs of the European Union, as well as with leading scientific centers, foundations, and societies.

Consumers interested in purchasing services for the treatment of patients with long-term non-protective wounds and trophic ulcers using mesembryonic stem cells and skin fibroblasts, including services using these methods for adult patients in accordance with the medical license under an outsourcing agreement.

Partners interested in purchasing services for the treatment of patients with long-term non-protective wounds and trophic ulcers using mesembryonic stem cells and skin fibroblasts, including services using these methods for adult patients in accordance with the medical license under a distribution services agreement.