The Institute of Bioorganic Chemistry offers consumers a medicinal product - the antitumor drug Pemetrexed on the basis of a manufacturing agreement, a technology for obtaining a substance on the basis of a license agreement and is looking for partners to conclude a distribution services agreement.

Pemetrexed disodium salt heptahydrate, pharmaceutical substance Pemetrexed, lyophilized powder for solution for infusion 500 mg. Antineoplastic agent, an analog of folic acid, antimetabolite, used for the treatment of locally advanced or metastatic non-squamous cell non-small cell lung cancer as the first line of therapy (in combination with cisplatin), for the treatment of previously treated patients (in mono-mode), as well as supportive therapy in patients with the non-progressive disease after primary therapy with platinum drugs.

A pilot production technology has been developed and the pharmaceutical substance Pemetrexed is registered disodium salt heptahydrate (FSP RB 2050-15; RU No. 15/02/2340).

A finished dosage form of Pemetrexed has been developed and registered (FSP RB 2099-15; RU No. 15/06/2401).

It is used in the treatment of inoperable pleural mesothelioma, in combination with platinum preparations.

The institute has an experimental base for studying the biological activity of the obtained compounds at the cellular level and in tests on animal models. For pilot production of the developed products (hemosorbents, preparations of recombinant enzymes, immunochemical reagents, oxyphitosterols, etc.), 5 experimental production sites have been created at the institute.

The results of fundamental and applied research on methods and means of protecting plants from diseases, insects, weeds, and other unfavorable environmental factors that are safe for humans and the biosphere as a whole were the basis for the development of methods for obtaining new plant growth stimulators, pheromone compositions (pheromones of the codling moth LP -U and mill moth), active ingredients of pesticides (analogs of the herbicide Grasp and insecticide Confidor), formulations of pesticides (herbicides, insecticides, fungicides, etc.).

The created intellectual property of the Institute today consists of patents maintained in force, laboratory technological and experimental industrial regulations, technical specifications, and trademarks. Licensing agreements are in force for the transfer of technologies for the production of immunodiagnostic products, hemosorbents and pesticides to manufacturers.

Consumers interested in purchasing the anticancer drug Pemetrexed under a manufacturing agreement.

Distributors interested in purchasing the anticancer drug Pemetrexed under a distribution services agreement.

Partners interested in acquiring technology for obtaining the substance of the anticancer drug Pemetrexed under a license agreement.