Phospholipid derivatives of modified nucleoside 6-tideoxyguanosine with antitumor activity
COUNTRY OF ORIGIN
IDENTIFIER
BO6495PUBLISHED
2023-03-16LAST UPDATE
2023-03-17DEADLINE
Linked profile in other language
Responsible
Tatiana Petkevich
zakupkibio@mail.ru
zakupkibio@mail.ru
Summary
The Institute of Microbiology offers consumers for research phospholipid derivatives of the modified nucleoside 6-tideoxyguanosine, which has an antitumor effect under a manufacturing agreement.
Description
Compounds potentially have improved antitumor properties compared to the original nucleoside. Once in the patient's body, the compounds are perceived by the telomerase of tumor cells as a substrate and instead of the natural nucleoside are inserted into the telomeres of the affected cells, which, thus, become altered and exposed to the body's immune system. Joint development with MAIA Biotechnology (USA). Preclinical tests have shown the formation of immune memory to a certain type of tumor. Clinical trials are currently underway.
Included in the Catalog of exhibits (TOP DEVELOPMENTS by exposition clusters) of the exhibition of scientific and technological achievements "Intellectual Belarus 2023".
Included in the Catalog of exhibits (TOP DEVELOPMENTS by exposition clusters) of the exhibition of scientific and technological achievements "Intellectual Belarus 2023".
Advantages and Innovations
Improved antitumor properties compared to the parent nucleoside.
Stage of development
Under development/lab tested (TRL4)
Funding source
State budged
Internal
Internal
IPR status
Exclusive rights
Secret know-how
Secret know-how
Sector group
BioChemTech
Healthcare
Healthcare
Organization information
Type
R&D institution
Year established
1975
NACE keywords
A.01.61 - Support activities for crop production
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
M.72.11 - Research and experimental development on biotechnology
M.72.19 - Other research and experimental development on natural sciences and engineering
M.74.90 - Other professional, scientific and technical activities n.e.c.
Turnover (in EUR)
10-20M
Already engaged in transnational cooperation
Yes
Additional comments
The Institute of Microbiology is the leading research center of the Republic of Belarus in the field of microbiology and biotechnology. The Institute's arsenal of innovative developments includes substances for medicines and diagnostics, biopreservatives, feed and food additives, biodisinfectants, probiotics, plant protection products, microbial fertilizers, wastewater and environmental treatment technologies that are in demand by the economy, and specific recommendations for combating biodamage.
Languages spoken
English
Russian
Russian
Information about partnership
Type of partnership considered
Manufacturing agreement
Type and role of partner sought
Consumers interested in purchasing for research phospholipid derivatives of the modified nucleoside 6-tideoxyguanosine, which has antitumor activity under a manufacturing agreement.
Type and size of partner sought
> 500
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
251-500
SME 51-250
SME 11-50
SME <= 10
R&D Institution
University
Attachments
Views: 1212
Statistics since 16.03.2023 14:20:32
Statistics since 16.03.2023 14:20:32