The Institute of Bioorganic Chemistry offers consumers kits of reagents for DNA identification of biological samples of wild animals of the order Artiodactyla under a manufacturing agreement and is looking for partners interested in a distribution services agreement.

Reagent kits for forensic DNA identification of biological samples of wild animals have been developed to meet the needs of the Investigative Committee of the Republic of Belarus and create an objective basis for compensating the state for direct and indirect (ecological) damage from the illegal seizure of wild animals.

The reagent kits "Artiodactyla Diff-PLEX" (TU BY 100185129.171-2019), "Sus ID-PLEX" (TU BY 100185129.172-2019), "Alces ID-PLEX" (TU BY 100185129.173-2019), "Cervus ID-PLEX" (TU BY 100185129.174-2019), "Capreolus ID-PLEX" (TU BY 100185129.175-2019) have been developed to establish the species affiliation of biological samples of wild animals of the Deer family (elk (genus Alces), roe deer (genus Capreolus), deer (genus Cervus)) and domestic animals of the Bovidae family (cattle (genus Bos), goat (genus Capra), sheep (genus Ovis)), as well as for identification of animal genotype, sex, establishment of belonging of biological traces to one or different animal individuals and biological relationship of animals (reliability of origin of offspring) for the following species: elk (Аlces alces), wild boar (Sus scrofa), European roe deer (Сapreolus сapreolus)
and genus Deer (Cervus sp.).

The developed new domestic production technology is based on multiplex genotyping of minisatellite (STR-) loci of DNA isolated from the identified sample with subsequent electrophoretic analysis of fluorescently labeled PCR products.

Information is posted in  Album of promising developments of the NAS of Belarus organizations for the real sector of the economy (2023), p. 179-180. (in Russian)

The kits are adapted for the ABI3130 and ABI3500 genetic analyzers widely used in forensic laboratories. In-house production allows us to quickly supply the required number of kits, and the manufacturer provides ongoing technical support.

There are no commercial analogues for the Artiodactyla Diff-PLEX, Cervus ID-PLEX, and Capreolus ID-PLEX kits.
In terms of sensitivity (0.5–1.0 ng DNA) and specificity (99.5%), they correspond to world analogues.

The use and application of the kits do not pose any environmental risks.

The technologies developed for the production of reagent kits are protected as a commercial secret.

Currently, the Institute of Bioorganic Chemistry of the National Academy of Sciences of Belarus is one of the well-known scientific centers for the study of the most important biopolymers (proteins, enzymes, nucleic acids) and low-molecular bioregulators (steroid hormones of humans, insects and plants, peptides, phospholipids, prostaglandins and their synthetic analogues).

Main areas of activity:
- fundamental and applied research in the field of chemistry, structure and function of biopolymers and low-molecular bioregulators, including proteins, nucleic acids and their components, phospholipids, steroids, prostaglandins, brassinosteroids, ecdysteroids;
- development and pilot production of immunochemical and molecular biological reagent kits for medical and veterinary diagnostics;
- development and production of pharmaceutical substances, hormonal drugs and biospecific hemosorbents;
- development of technologies for the production and use of growth stimulants and plant protection products;
- experimental and clinical pharmacology, pharmacy and drug technology, toxicology, human and animal biochemistry, biomedical and pharmaceutical chemistry;
- preclinical, bioequivalent and pharmaceutical testing.

Main research areas:
- organic and bioorganic chemistry of low-molecular bioregulators (steroids, peptides, prostaglandins, lipids, nucleosides and nucleotides) and the most important biopolymers, including proteins and nucleic acids, establishing patterns of their functioning in living systems;
- development of new chemical, chemical-enzymatic and genetic engineering methods for obtaining biopolymers and low-molecular bioregulators and their analogues in order to create drugs for medicine and agriculture on their basis;
- study of the structure, physicochemical properties and biological activity of natural biomolecules and their analogues, establishing the relationship between their structure and biological activity, development of scientific principles for targeted search for substances with predictable biological activity;
- study of the structure, function and mechanism of action of enzyme systems of biosynthesis and metabolism of the most important natural bioregulators and xenobiotics;
- development of technologies for the production of reagents for medical diagnostics, drugs and chemical plant protection products.

The institute has an experimental base for studying the biological activity of the obtained compounds at the cellular level and in tests on animal models. For the pilot production of the developed products (hemosorbents, recombinant enzyme preparations, immunochemical reagents, oxyphytosterols, etc.), the institute has created 5 pilot production sites.

The results of fundamental and applied research on methods and means of plant protection against diseases, insects, weeds and other adverse environmental factors that are safe for humans and the biosphere as a whole served as the foundation for developing methods for obtaining new plant growth stimulants, pheromone compositions (pheromones of the codling moth LP-U and the miller moth), active ingredients of pesticides (analogues of the herbicide Grasp and the insecticide Confidor), preparative forms of pesticides (herbicides, insecticides, fungicides, etc.).

The created intellectual property of the Institute today consists of valid patents, laboratory technological and pilot-industrial regulations, technical specifications, and trademarks. There are license agreements in force for the transfer of technologies for the production of immunodiagnostic products, hemosorbents and pesticides to manufacturers.

The Institute of Bioorganic Chemistry successfully develops international relations in the main areas of its research. Currently, the institute conducts joint research with scientific institutes in the CIS countries, Germany, the USA, Canada, Sweden, Finland, Denmark, Holland, Vietnam and other countries.

Consumers interested in purchasing reagent kits for DNA identification of biological samples of wild animals of the order Artiodactyla under a manufacturing agreement.

Partners interested in purchasing reagent kits for DNA identification of biological samples of wild animals of the order Artiodactyla under a distribution services agreement.