Institute of Physical Organic Chemistry offers customers modified controlled pore glass (CPG) for the automated synthesis of modified DNA and RNA oligonucleotides under a manufacturing agreement and is seeking partners interested in a distribution services agreement.

Application area.
1. Synthesis of modified DNA oligonucleotides, including fluorescent DNA probes for PCR diagnostics.
2. Synthesis of modified RNA oligonucleotides for molecular biological and genetic research, development of drugs for gene therapy.

In terms of purity, they are not inferior to imported analogues. Efficiency in oligosynthesis is confirmed by analytical data, positive consumer reviews and constant demand. The technology allows obtaining carriers with a wide range of modifications using reagents of our own production.

Environmentally friendly.

The CPG production technology does not involve the use of complex specialized equipment, can be scaled up and adapted for the production of a wide range of modifications.

The obtained reagents, DNA probes and bioconjugates have been tested in research laboratories of the Republic of Belarus, the Russian Federation, the USA and Germany. The results have been published in prestigious international publications.

The Institute is a world leader in the development, production and use of ion-exchange fibrous materials and artificial substrates for plant cultivation. The Institute's work in the field of membranes and membrane technologies is widely known. Membrane materials for ultra- and microfiltration in the form of continuous webs and capillaries, cassette, roll and hollow fiber elements for use in energy, food, pharmaceutical, electronic and other industries have been developed and manufactured.

The Institute's scientists have discovered and studied the reactions of: heterocyclization of azomethines with carbonyl compounds, hydroamination of oxygen-containing compounds, initiated decarboxylation of mercury acylates, construction of an isothiazole cycle from 2-nitropentachlorobutadiene and sulfur. Convenient methods for synthesizing benzoquinolines, amines, pyridines, organomercury compounds, electrochemical methods for obtaining p-complexes of transition metals, methods for synthesizing various functional substituted organohalogen compounds, carboranes and peroxides have been developed.

The catalysts developed at the Institute have been implemented at the largest chemical plants. An antiblock composition preventing cellophane film from sticking together during its production has been implemented on an industry-wide scale. An industrial radiation-chemical technology for obtaining the blood plasma substitutes "Rondeks" and "Neorondex" has been developed.

The Institute's activities are aimed at developing scientific principles and technologies for creating new polymeric materials with special properties (selectively permeable, sorption, ion-exchange, catalytically active) for use in industry, ecology, agriculture, water treatment; development of methods for the synthesis and technologies for obtaining medicinal substances based on amino acids and their derivatives, biologically active substances and compositions for medicine and agriculture, functionally substituted organic and organoelement compounds.

The Institute carries out international scientific and technical cooperation within the framework of direct agreements with scientific institutions of Russia, Ukraine, Germany, Poland, Sweden, China, etc. Much attention is paid to the implementation of contracts for the conduct of research and development work and the manufacture of high-tech commercial products based on its own developments with organizations and firms in Saudi Arabia, Germany, Korea, Russia, and the USA.

Customers interested in purchasing modified controlled pore glass (CPG) for automated synthesis of modified DNA and RNA oligonucleotides under a manufacturing agreement.

Partners interested in purchasing modified controlled pore glass (CPG) for automated synthesis of modified DNA and RNA oligonucleotides under a distribution services agreement.